Pulling on a cytokine

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Pulling on a cytokine

In This Issue In This Issue Pulling on a cytokine he extracellular matrix (ECM) acts as a storage facility for tons of factors waiting to do business in the cell. Annes et al. (page 723) show that the ECM anchoring of one factor, the cytokine TGF-␤ , is essential for its activation. The anchoring may give cells something to pull against, with the pulling mediating the activation. Most TGF-␤ is ...

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ژورنال

عنوان ژورنال: Journal of Cell Biology

سال: 2004

ISSN: 1540-8140,0021-9525

DOI: 10.1083/jcb1655iti1